The route of the race is from north to south, from Icacal in the Caribbean to Playa Blanca in the Pacific. The route crosses the continental divide of Panama at La Mesa before going down to El Valle de Antón and continuing to the beach.
This was the route for 2021:
The Route for the 2022 Race will be shared before the race. It is 100miles Ocean to Ocean and meets the man made Gatun Lake that feeds the water for the Panama Canal